Infant formulas for early brain development

A - Human Necessities – 23 – L

Patent

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Details

A23L 1/29 (2006.01) A23L 1/30 (2006.01) A23L 1/305 (2006.01) A61K 31/202 (2006.01) A61K 31/685 (2006.01) A61K 31/7032 (2006.01) A61P 25/00 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2656170

Disclosed are infant formulas comprising at least about 6.5 g/L, on an as-fed basis, of an enriched whey protein concentrate, at least about 0.13% docosahexaenoic acid by weight of total fatty acids, and at least about 0.25% arachidonic acid by weight of total fatty acids. The formulas also typically include at least about 5 mg/L of gangiiosides, at least about 150 mg/L of phospholipids, and at least about 70 mg/L of total sialic acid with at least about 2.5% as iipid-bound sialic acid, all of which are provided in whole or in part from the enriched whey protein concentrate. Also disclosed are methods of accelerating brain development, neural migration, and cognitive development in an infant by administering the infant formulas during the first 2-4 months of life, preferably as a sole source of nutrition.

L'invention concerne des préparations pour nourrissons comprenant environ 6,5 g/L, à consommer tel quel d'un concentré enrichi de protéine de lactosérum, au moins environ 0,13 % du total des acides gras en poids d'acide docosahexaénoïque, et au moins environ 0,25 % du total des acides gras en poids d'acide arachidonique. Les préparations incluent également au moins 5 mg/L de gangliosides, au moins environ 150 mg/L de phospholipides, et au moins environ 70 mg/L d'acide sialique total avec au moins environ 2,5 % sous forme d'acide sialique lié à des lipides, tous étant fournis en totalité ou en partie à partir du concentré enrichi de protéine de lactosérum. L'invention concerne également des procédés pour accélérer le développement du cerveau, la migration des neurones et le développement cognitif chez un nourrisson par l'administration des préparations pour nourrisson pendant les premiers 2 à 4 mois de la vie, de préférence en tant que source unique d'alimentation.

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