A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 39/02 (2006.01) A61L 29/00 (2006.01) A61L 29/16 (2006.01) A61M 25/00 (2006.01)
Patent
CA 2168729
The present invention provides for medical devices which are antiinfective as a result of antiinfective agents impregnated onto their surfaces and/or antiinfective activity incorporated into their access sites. It is based, at least in part, on the discovery that certain combinations of antimicrobial agents and solvents change the surface characteristics of polymeric medical devices, thereby facilitating the retention of antimicrobial agents. It is further based on the discovery that the incorporation of antiinfective polymeric inserts into the access site of a medical device provides substantially improved antiinfective activity.
L'invention concerne des dispositifs médicaux qu'on rend anti-infectieux en imprégnant leurs surfaces d'agents anti-infectieux et/ou en rendant leurs régions de contact anti-infectieuses. L'invention est basée, au moins partiellement, sur la découverte que certaines combinaisons d'agents antimicrobiens et de solvants modifient les caractéristiques de surface de dispositifs médicaux polymères, ce qui facilite la rétention d'agents antimicrobiens. Elle est, de plus, basée sur la découverte que l'incorporation de pièces polymères anti-infectieuses dans la région de contact d'un dispositif médical permet d'améliorer sensiblement l'efficacité anti-infectieuse.
Modak Shanta
Sampath Lester
G. Ronald Bell & Associates
The Trustees Of Columbia University In The City Of New York
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