Infectious and attenuated bovine viral diarrhea virus clone;...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/04 (2006.01) A61K 39/12 (2006.01) C07K 14/08 (2006.01) C07K 14/18 (2006.01) C12N 7/00 (2006.01)

Patent

CA 2457441

The invention belongs to the field of animal health and in particular Bovine Viral Diarrhea Virus (BVDV). The invention provides infectious BVDV clones and methods to produce said BVDV clones. The invention further relates to methods of attenuating said clones, attenuated BVDV clones and vaccines comprising said attenuated clones.

L'invention se rapporte au domaine de l'hygiène vétérinaire, et plus particulièrement au virus de diarrhée virale bovine (BVDV). L'invention concerne des clones infectieux du BVSV et des procédés permettant de produire lesdits clones de BVDV. L'invention concerne en outre des procédés permettant d'atténuer lesdits clones, des clones de BVDV atténués et des vaccins comprenant lesdits clones atténués.

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