C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/40 (2006.01) A61K 39/12 (2006.01) C07K 14/08 (2006.01) C12N 5/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2272046
The invention comprises a method for generating an infectious clone based on the genome of a positive strand RNA virus which has a genome of at least about 15 kb. The invention further comprises a method for generating an infectious clone based on the genome of an RNA virus, said method further comprising selecting infectious clones by transfecting a host cell with said recombinant nucleic acid whereby said host cell is in essence not susceptible to infection with said virus. The invention further provides modified RNA viruses and vaccines and diagnostic assays derived thereof.
L'invention concerne un procédé permettant de produire un clone infectieux basé sur le génome d'un virus à ARN à brin positif présentant un génome d'au moins environ 15 kb. L'invention concerne également un procédé permettant de produire un clone infectieux basé sur le génome d'un virus à ARN, ledit procédé consistant à sélectionner des clones infectieux par transfection d'une cellule hôte avec ledit acide nucléique recombiné, de manière que la cellule hôte soit par essence non susceptible d'une infection par ledit virus. L'invention concerne en outre des virus à ARN modifiés ainsi que des vaccins et des titrages de diagnostics dérivés.
Bos-De Ruijter Judy Norma Aletta
Meulenberg Johanna Jacoba Maria
Pol Johannes Maria Antonius
Boehringer Ingelheim Vetmedica Gmbh
Borden Ladner Gervais Llp
Stichting Dienst Landbouwkundig Onderzoek
LandOfFree
Infectious clones of rna viruses and vaccines and diagnostic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Infectious clones of rna viruses and vaccines and diagnostic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Infectious clones of rna viruses and vaccines and diagnostic... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1496328