C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/04 (2006.01) A61K 39/29 (2006.01) C07K 14/18 (2006.01) C12N 15/86 (2006.01) C12Q 1/70 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2498770
The invention relates to the generation and the use of hepacivirus pseudo- particles containing native functional E1, E2 envelope glycoproteins assembled onto retroviral core particles. These particles are highly infectious and constitute a valid model of hepacivirus viríon.
L'invention concerne l'élaboration et l'utilisation de pseudo-particules d'hépacivirus renfermant des glycoprotéines fonctionnelles naturelles d'enveloppe E1, E2 assemblées sur des particules-coeurs rétrovirales. Ces particules sont hautement infectieuses et constituent un modèle valide de virion d'hépacivirus.
Bartosch Birke
Cosset Francois-Loic
Ecole Normale Superieure de Lyon
Institut National de La Sante Et de La Recherche Medicale (inser
Robic
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