Inflammation targeting particles

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/51 (2006.01)

Patent

CA 2747318

Opsonizable micro- or nanoparticles, that contain at least one active agent, such as an imaging or therapeutic agent; that have a positive surface charge and that do not contain on their surface targeting ligands, such as antibodies, peptides or aptamers, can be used to treating and/or monitoring a condition associated with an inflammation, such as a cytokine stimulated inflammation.

L'invention concerne des micro- ou nanoparticules pouvant subir une opsonisation, lesdites particules contenant au moins un principe actif, par exemple un agent d'imagerie ou thérapeutique; lesdites particules présentant une surface chargée positivement et ne portant pas à leur surface de ligands ciblants, par exemple des anticorps, des peptides ou des aptamères, peuvent être employées dans le traitement et/ou la surveillance d'un état pathologique associé à une inflammation, par exemple une inflammation stimulée par des cytokines.

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