Inflammatory cell inhibitors

Details Inflammatory cell inhibitors Inflammatory cell inhibitors

A - Human Necessities

61

K

A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01) A61K 31/223 (2006.01) A61K 31/34 (2006.01) A61K 31/341 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2322486

Compounds of general formula (I), wherein R4 is an ester or thioester group and R, R1, R2 and R3 are as specified in the description, inhibit monocyte and/or macrophage and/or lymphocyte activation and lymphocyte proliferation.

L'invention concerne des composés de la formule générale (I) dans laquelle R¿4? est un groupe ester ou thioester; et R, R¿1?, R¿2? et R¿3? sont tels que définis dans le mémorandum descriptif. Ces composés inhibent l'activation des monocytes et/ou des macrophages et/ou des lymphocytes ainsi que la prolifération lymphocytaire.

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