Inflammatory cytokine release inhibitor

Details Inflammatory cytokine release inhibitor Inflammatory cytokine release inhibitor

C - Chemistry, Metallurgy

07

D

C07D 277/32 (2006.01) A61K 31/00 (2006.01) C07C 39/00 (2006.01) C07C 49/00 (2006.01) C07C 69/00 (2006.01) C07C 215/00 (2006.01) C07C 233/00 (2006.01) C07C 235/64 (2006.01) C07C 243/24 (2006.01) C07C 245/00 (2006.01) C07C 251/00 (2006.01) C07C 255/00 (2006.01) C07C 309/00 (2006.01) C07C 311/00 (2006.01) C07C 335/00 (2006.01) C07D 207/00 (2006.01) C07D 209/00 (2006.01) C07D 211/00 (2006.01) C07D 213/00 (2006.01) C07D 215/00 (2006.01) C07D 239/00 (2006.01) C07D 241/00 (2006.01) C07D 263/00 (2006.01) C07D 285/1

Patent

CA 2431083

A medicament having inhibitory activity against NF- .kappa. B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: (see formula I) wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.

L'invention concerne des médicaments à activité d'inhibition de l'activation du NF-kB, contenant comme ingrédient actif des composés représentés par la formule générale (I) (dans laquelle X est un groupe de connexion, A est hydrogène ou acétyle, E est aryle ou hétéroaryle, et Z est arène ou hétéroarène) ou des sels de ceux-ci acceptables d'un point de vue pharmacologique: (I)

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