Influenza b viruses having alterations in the hemaglutinin...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/44 (2006.01) A61K 39/145 (2006.01) C07K 14/11 (2006.01) C12N 7/00 (2006.01) C12N 15/09 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2690196

The present invention encompasses methods of producing influenza B viruses in cell culture. The influenza B viruses may have desirable characteristics, such as enhanced replication in eggs and may be used, for example, in vaccines and in methods of treatment to protect against influenza B virus infection.

La présente invention a pour objet des procédés de production des virus B de la grippe en culture cellulaire. Les virus B de la grippe peuvent présenter des caractéristiques souhaitables, telles qu'une amplification de la réplication dans les ufs et ils peuvent servir, par exemple, dans des vaccins et dans des procédés de traitement destinés à protéger contre une infection par le virus B de la grippe.

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