Influenza vaccine

Details Influenza vaccine Influenza vaccine

A - Human Necessities

61

K

A61K 39/145 (2006.01) A61P 31/12 (2006.01) C12N 7/02 (2006.01)

Patent

CA 2386014

The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.

L'invention concerne un vaccin monovalent contre la grippe comprenant une faible dose d'antigène du virus de la grippe dérivé de l'oeuf, d'une souche de virus associée à une pandémie ou ayant le potentiel d'être associée à une pandémie, combinée à un adjuvant aluminium. L'invention concerne également des kits de vaccins comprenant une combinaison de vaccins contre la grippe parentéraux et des muqueuses, dans lesquels la dose combinée d'antigène n'est pas supérieure à la dose d'antigène habituelle. L'invention concerne également des procédés de préparation des vaccins.

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