Influenza vaccine compositions and method for immunization...

Details Influenza vaccine compositions and method for immunization... Influenza vaccine compositions and method for immunization...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/145 (2006.01)

Patent

CA 2603180

The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particular, the invention relates to multivalent influenza immunogenic compositions comprising an influenza antigen or antigenic preparation thereof from at least two influenza virus strains, at least one strain being associated with a pandemic outbreak or having the potential to be associated with a pandemic outbreak, in combination with an oil-in-water emulsion adjuvant.

La présente invention concerne des formulations de vaccin contre la grippe et des régimes de vaccination pour l~immunisation contre la maladie de la grippe, leur utilisation en médecine, en particulier leur utilisation dans l~augmentation des réponses immunes à divers antigènes, et des procédés de préparation. En particulier, l~invention concerne des compositions immunogènes multivalentes de grippe comprenant un antigène de la grippe ou sa préparation antigénique à partir d~au moins deux souches de virus de la grippe, au moins une souche étant associée avec une poussée pandémique ou pouvant être associée avec une poussée pandémique, en combinaison avec un adjuvant de type émulsion huile dans l~eau.

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