Influenza virus infection suppressor

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61P 31/16 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2559067

It is intended to provide an influenza virus-infection inhibitor which contains a sialylgalactose group-binding peptide (for example, a ganglioside GM3-binding peptide) as the active ingredient. More specifically speaking, it is intended to provide an influenza virus-infection inhibitor which contains the following sialylgalactose group-binding peptide (a) or (b) as the active ingredient. (a) A peptide comprising an amino acid sequence represented by SEQ ID NO:1 or 2. (b) A peptide containing an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:1 or 2 by deletion, substitution or addition of one to several amino acids and having an activity of binding to sialylgalactose group.

Il est prévu de fournir un inhibiteur de l'infection par le virus de la grippe qui contient un peptide qui se lie au groupe sialylgalactose (par exemple, un peptide qui se lie au ganglioside GM3) en tant qu'ingrédient actif. Plus particulièrement, il est prévu de fournir un inhibiteur de l'infection par le virus de la grippe qui contient le peptide (a) ou (b) suivant qui se lie au groupe sialylgalactose en tant qu'ingrédient actif. (a) Peptide qui comprend une séquence d'acides aminés représentée par SEQ ID n° 1 ou 2. (b) Peptide qui contient une séquence d'acides aminés dérivée d'une séquence d'acides aminés représentée par SEQ ID n° 1 ou 2 par suppression, substitution ou addition d'un à plusieurs acides aminés et qui a une activité de fixation au groupe sialylgalactose.

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