C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 39/145 (2006.01)
Patent
CA 2250716
The invention provides replication of high growth influenza virus strains, derived from clinical isolates, in cultured mammalian cells by infecting the mammalian cells with the high growth strains to obtain infected cells, and culturing the cells while maintaining a trypsin concentration range of 0.05- 1.0 µg/ml in the culture medium, where the resulting replicated virus is suitable for use in mammalian influenza vaccines and vaccination methods, which are also provided by the invention.
Réplication de souches de virus de grippe à forte croissance obtenues à partir d'isolats cliniques dans des cultures de cellules de mammifères par contamination de ces cellules à l'aide de ces souches à forte croissance pour obtenir des cellules infectées et culture de ces cellules avec maintien d'une concentration de trypsine dans la plage des 0,05 - 1,0 µg/ml dans le milieu de culture, de manière à obtenir un virus répliqué se prêtant à une utilisation dans des vaccins contre la grippe chez les mammifères. L'invention porte également sur des méthodes de vaccination.
Kaverin Nicolai V.
Webster Robert G.
Mbm Intellectual Property Law Llp
St. Jude Children's Research Hospital
LandOfFree
Influenza virus replicated in mammalian cell culture and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Influenza virus replicated in mammalian cell culture and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Influenza virus replicated in mammalian cell culture and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1996987