Inhalable aztreonam for treatment and prevention of...

A - Human Necessities – 61 – K

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A61K 31/427 (2006.01) A61K 9/19 (2006.01) A61P 11/00 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2708703

A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug reistant Pseudomonas aeruginosa, using a concentrated formulation of aztreozonam, or a pharmaceutically acceptable salt thereof, delivered as an aerosol or dry powder formulation.

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