Inhalant formulations comprising a bisphosphonate and a...

Details Inhalant formulations comprising a bisphosphonate and a... Inhalant formulations comprising a bisphosphonate and a...

A - Human Necessities

61

K

A61K 31/4152 (2006.01) A61P 19/08 (2006.01) A61K 9/72 (2006.01) A61K 31/663 (2006.01)

Patent

CA 2734283

The present invention provides for methods of administering by a pulmonary route a bisphosphonate active agent in combination with a pyrazolone derivative to a subject. Also provided are pharmaceutical compositions for use in practicing methods according to embodiments of the invention. The methods and compositions according to embodiments of the invention find use in a variety of different applications, including but not limited to, the treatment of bone absorption disease conditions.

La présente invention porte sur des méthodes d'administration à un sujet par voie pulmonaire d'un agent actif de bisphosphonate en combinaison avec un dérivé de pyrazolone. L'invention porte également sur des compositions pharmaceutiques à utiliser dans la pratique de méthodes selon des modes de réalisation de l'invention. Les méthodes et compositions selon les modes de réalisation de l'invention trouvent une utilité dans toute une gamme dapplications, comprenant, mais sans s'y limiter, le traitement d'états d'ostéolyse.

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