Inhalation compositions with high drug ratios

Details Inhalation compositions with high drug ratios Inhalation compositions with high drug ratios

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 9/14 (2006.01) A61K 9/72 (2006.01)

Patent

CA 2499280

The invention provides a dry powder inhalation composition comprising, at least 0.25% by weight of the composition of an active ingredient with a particle size of less than 10 microns in diameter and a pharmaceutically acceptable particulate carrier with a particle size of less than 250 microns in diameter. Also disclosed are methods for use of the compositions of the invention with dry powder inhalers for therapeutic treatments.

L'invention se rapporte à une composition pour inhalation à base de poudres sèches comportant, par rapport au poids total de la composition, au moins 0,25 % en poids d'un principe actif ayant des particules de diamètre inférieur à 10 microns et un excipient particulaire pharmaceutiquement acceptable ayant des particules de diamètre inférieur à 250 microns. L'invention se rapporte également à des procédés d'utilisation de ces compositions avec des dispositifs pour inhalation de poudres sèches mis en oeuvre dans des traitements thérapeutiques.

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