C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2361335
The invention features a method of inhibiting formation of atherosclerotic lesions by administering to a mammal, e.g., a human patient who has been identified as suffering from or at risk of developing atherosclerosis, a compound that reduces expression or activity of AFABP.
La présente invention concerne un procédé visant à inhiber la formation de lésions athéroscléreuses. Ce procédé consiste notamment en l'administration d'un composé réduisant l'expression ou l'activité de l'AFABP (adipocyte fatty acid binding protein). Les sujets concernés par une telle administration sont des mammifères, et plus particulièrement des humains souffrant d'athérosclérose ou susceptibles d'en développer.
Haber Edgar
Hotamisligil Gokhan S.
Lee Mu-En
Perrella Mark A.
Kirby Eades Gale Baker
President And Fellows Of Harvard College
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