Inhibiting photodecomposition of 3-substituted-2-oxindoles

Details Inhibiting photodecomposition of 3-substituted-2-oxindoles Inhibiting photodecomposition of 3-substituted-2-oxindoles

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 31/404 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07D 209/34 (2006.01) C07D 409/12 (2006.01) C09K 15/00 (2006.01)

Patent

CA 2216931

This invention relates to the protection of certain 3-substituted-2-oxindole-1- carboxamides of formula (I) and the pharmaceutically-acceptable base salts thereof wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl, each optionally substituted with Cl or F from decomposition in the presence of light.

L'invention concerne la protection de certains 2-oxindoles-1-carboxamides-3-substitués-3, selon la formule (I), et leurs sels basiques pharmaceutiquement acceptables. Dans ladite formule, X représente H, Cl ou F; Y représente H ou Cl; et R représente benzyle ou thiényle, chacun étant éventuellement substitué par Cl ou F suite à la décomposition en présence de lumière.

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