C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 31/195 (2006.01) A61K 31/415 (2006.01) A61K 31/505 (2006.01) A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) C07K 14/82 (2006.01) C12N 9/12 (2006.01) C12N 15/11 (2006.01) C12Q 1/48 (2006.01) C12Q 1/50 (2006.01) G01N 33/574 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2046607
A method of inhibiting growth rate, transformation or metastasis of mammalian cells, particularly epithelial cells, in which activity of at least one enzyme which participates in purine metabolism and regulation of nucleotide levels is elevated. In particu- lar, a method of inhibiting transformation of mammalian cells by a DNA tumor virus, a DNA tumor virus factor or other factor which has an equivalent effect on cells.
Daouk Ghaleb
Green Michael
Kaddurah-Daouk Rima
Kingston Robert
Lillie James W.
Amira Inc.
Harvard University
Massachusetts Institute Of Technology
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The General Hospital Corporation
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