Inhibition of a novel calcium injury current that forms in...

A - Human Necessities – 61 – K

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Details

A61K 33/24 (2006.01) A01N 43/04 (2006.01) A61K 31/355 (2006.01) A61K 31/375 (2006.01) A61K 31/385 (2006.01) A61K 31/727 (2006.01) A61K 33/00 (2006.01)

Patent

CA 2404157

Calcium channels which form in neuronal membranes in response to injury are disclosed. Methods and compositions for blocking this injury induced calcium channel and preventing further injury to neuronal cells and/or neuronal cell death are disclosed. The compositions and methods disclosed may be used to alleviate acute or chronic injury to neuronal cells.

L'invention se rapporte à des canaux calciques qui se forment dans les membranes neuronales en réponse à une lésion. L'invention se rapporte également aux procédés et aux compositions destinés à bloquer ces canaux calciques induits lors d'une lésion et à prévenir des lésions subséquentes dans les cellules neuronales et/ou la mort de celles-ci. Lesdits procédés et compositions peuvent être utilisés afin de soulager des lésions aiguës ou chroniques des cellules neuronales.

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