Inhibition of angiogenesis

Details Inhibition of angiogenesis Inhibition of angiogenesis

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/255 (2006.01) A61K 31/4015 (2006.01) A61K 31/44 (2006.01) A61K 31/4412 (2006.01)

Patent

CA 2323490

Certain simple chemical agents, referred to herein as nitrone related therapeutics or "NRTs", when administered to a patient susceptible to neovascularization (angiogenesis), can intervene and inhibit the disease's progress. Methods for therapeutically and prophylactically inhibiting angiogenesis by administering one or more NRTs are disclosed as are pharmaceutical compositions for use in such methods of treating. NRTs useful in these compositions and therapeutic methods are also disclosed.

Certains agents chimiques simples, désignés en tant qu'agents thérapeutiques apparentés à nitrone ou "NRT", quand on les administre à un patient susceptible de néovascularisation (angiogenèse), peuvent intervenir et inhiber la progression de la maladie. L'invention concerne des procédés servant à inhiber l'angiogenèse, sur le plan thérapeutique et prophylactique, par administration d'un ou de plusieurs NRT, ainsi que des compositions pharmaceutiques mises en application dans ces procédés de traitement. Elle concerne également des NRT utiles pour ces compositions et ces procédés thérapeutiques.

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