A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/04 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01)
Patent
CA 2304108
A method for inhibiting caspase-mediated apoptosis by administering prosaposin receptor agonists is provided. Apoptosis has a major causative role in diseases such as rheumatoid arthritis, irritable bowel syndrome, congestive heart failure, multiple sclerosis, Alzheimer's disease, Parkinson's disease, myocardial infraction, and coronary ischemia.
L'invention concerne un procédé permettant d'inhiber l'apoptose liée à la caspase, par l'administration d'agonistes du récepteur de la prosaposine. L'apoptose constitue un facteur causal majeur dans des maladies telles que la polyarthrite rhumatoïde, le syndrome du côlon irritable, l'insuffisance cardiaque globale, la sclérose en plaques, la maladie d'Alzheimer, la maladie de Parkinson, l'infarctus du myocarde et l'ischémie coronarienne.
Kirby Eades Gale Baker
The Regents Of The University Of California
LandOfFree
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