Inhibition of bright function as a treatment for excessive...

C - Chemistry – Metallurgy – 07 – H

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Details

C07H 21/04 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2556849

The present invention involves the identification of Bright as involved in immunoglobulin production, and the targeting of that function for the treatment of disease states associated with pathologic immunoglobulin production. Also provided are methods of identifying candidate substances with Bright-inhibitory activity.

L'invention concerne l'identification du rôle de la fonction de Bright dans la production d'immunoglobulines ainsi que le ciblage de cette fonction afin de traiter les états pathologiques associés à une production pathologique d'immunoglobulines. L'invention concerne également des méthodes qui permettent d'identifier des substances candidates présentant une activité inhibitrice de la fonction de Bright.

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