Inhibition of cyclooxygenase-2 activity

Details Inhibition of cyclooxygenase-2 activity Inhibition of cyclooxygenase-2 activity

A - Human Necessities

61

K

A61K 31/454 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2404152

The present invention provides new methods for inhibiting the activity of the enzyme cycloxygenase-2 (or COX-2). Inhibitors of COX-2 are known to be useful anti-inflammatory, analgesic and anti-angiogenic agents. The compounds in the present case are heterocyclic substituted 4-aminoglutarimides. Methods of using the compounds to inhibit prostaglandin synthesis are claimed.

L'invention concerne de nouvelles méthodes d'inhibition de l'activité de l'enzyme cyclooxygénase-2 (ou COX-2). Les inhibiteurs de COX-2 sont utiles en tant qu'agents anti-inflammatoires, analgésiques et anti-angiogéniques. Les composés de l'invention sont des 4-aminoglutarimides hétérocycliques substitués. Des méthodes utilisant les composés d'inhibition de la synthèse de prostaglandine sont revendiquées.

Affiliated with

Also associated with

Rating

Inhibition of cyclooxygenase-2 activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibition of cyclooxygenase-2 activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of cyclooxygenase-2 activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1447353