Inhibition of fc.gamma.r-mediated phagocytosis with reduced...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2639003

The invention relates to pharmaceutical compositions for inhibiting Fc.gamma.R- mediated phagocytosis comprising a reduced immunoglobulin inhibitor of Fc.gamma.R- mediated phagocytosis, such as anti-D, in combination with a pharmaceutically acceptable carrier. The invention also relates to methods for treating or preventing an autoimmune or alloimmune disease comprising administering to a subject in need thereof a therapeutically effective amount of a reduced immunoglobulin inhibitor of Fc.gamma.R-mediated phagocytosis.

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