Inhibition of glial cell proliferation

Details Inhibition of glial cell proliferation Inhibition of glial cell proliferation

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2206321

Methods and compositions are disclosed that are useful for the inhibition of glial cell proliferation by means of binding inhibiting agents to neural cell adhesion (N-CAM) molecules present on the cell surface. Such inhibiting agents can be peptides, monoclonal antibodies, polyclonal antibodies, Fab' fragments, and the like.

L'invention concerne des procédés et des compositions efficaces pour l'inhibition de la prolifération de cellules gliales au moyen de la fixation d'agents d'inhibition à des molécules d'adhésion (N-CAM) aux cellules neurales présentes sur la surface de la cellule. Ces agents d'inhibition peuvent être des peptides, des anticorps monoclonaux, des anticorps polyclonaux, des fragments de Fab', par exemple.

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