Inhibition of herpesviridae infection by antisense...

Details Inhibition of herpesviridae infection by antisense... Inhibition of herpesviridae infection by antisense...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2089476

2089476 9203051 PCTABS00010 Antisense oligomers which are complementary to vital regions of a viral genome or mRNA transcripts thereof which exhibit antiviral activity are provided. Methylphosphonate oligomers complementary to particular sequences of herpes simplex virus type 1("HSV-1") messenger RNA have demonstrated antiviral activity. Methods of inhibiting viral replication using these oligomers are provided.

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