Inhibition of hiv mucosal infection

Details Inhibition of hiv mucosal infection Inhibition of hiv mucosal infection

C - Chemistry, Metallurgy

12

N

C12N 9/10 (2006.01) A61K 9/127 (2006.01) A61K 39/21 (2006.01) A61K 39/385 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2169453

Disclosed is a method of inhibiting the entry of HIV into the vaginal and rectal mucosal epithelium by administering a peptide vaccine. Antibodies generated against peptides corresponding to epitopes of gp120 involved in entry into mucosal cells are generated in vivo by introduction of peptides or peptide-cholera toxin conjugates into epithelial cells. The resulting neutralizing antibodies are able to block subsequent infection of these tissues by HIV.

Méthode d'inhibition de la pénétration du VIH dans l'épithélium des muqueuses vaginales et rectales par administration d'un vaccin peptidique. Les anticorps produits contre les peptides qui correspondent aux épitopes de la gp120 impliqués dans la pénétration dans des cellules épithéliales le sont in vivo par introduction de peptides et de conjugués de peptides et de toxines cholériques dans des cellules épithéliales. Les anticorps neutralisant résultant onla capacité de bloquer les infections subséquentes de ces tissus par le VIH.

Affiliated with

Also associated with

Rating

Inhibition of hiv mucosal infection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibition of hiv mucosal infection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of hiv mucosal infection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1489176