Inhibition of infection of mammalian cells by respiratory...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A23C 9/152 (2006.01) A23L 1/305 (2006.01) A61K 38/01 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2190609

The infection of mammalian cells by RSV may be inhibited by native human .beta.-casein, a recombinant form of human .beta.-casein, and hydrolysates of both. The human .beta.-casein or hydrolysate may be contained in a liquid enteral nutritional product such as an infant formula. The enteral nutritional product may be used, for example, in the prevention and treatment of respiratory tract infection in infants. The human .beta.-casein or hydrolysate may also be administered as a throat spray or nasally using drops or a spray.

L'infection de cellules de mammifères par la virus respiratoire syncytial RSV peut être empêchée par la .beta.-caséine humaine native, par une forme recombinée de .beta.-caséine humaine et par des hydrolysats de l'une et l'autre. La .beta.-caséine humaine ou son hydrolysat peuvent être contenus dans un produit d'alimentation entérale liquide, tel que du lait maternisé. Ce produit d'alimentation entérale peut être utilisé par exemple pour prévenir et traiter les infections des voies respiratoires chez les nourrissons. La .beta.-caséine humaine ou son hydrolysat peuvent également être administrés sous la forme d'un spray pour la gorge ou par voie nasale en gouttes ou en spray.

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