Inhibition of inflammatory cytokine production by...

Details Inhibition of inflammatory cytokine production by... Inhibition of inflammatory cytokine production by...

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2408791

A method of inhibiting the release of a proinflammatory cytokine in a cell is disclosed. The method comprises treating the cell with a cholinergic agonist. The method is useful in patients at risk for, or suffering from, a condition mediated by an inflammatory cytokine cascade, for example endotoxic shock. The cholinergic agonist treatment can be effected by stimulation of an efferent vagus nerve fiber, or the entire vagus nerve.

L'invention concerne un procédé permettant d'inhiber la libération d'une cytokine pro-inflammatoire dans une cellule. Le procédé consiste à traiter la cellule au moyen d'un agoniste cholinergique. Le procédé est utile chez des patients présentant un risque de développer une condition induite par une cascade de cytokines inflammatoires, par exemple un choc endotoxique, ou souffrant d'une telle condition. Le traitement aux agonistes cholinergiques peut être effectué par stimulation d'une fibre efférente du nerf vague, ou du nerf vague entier.

Affiliated with

Also associated with

Rating

Inhibition of inflammatory cytokine production by... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibition of inflammatory cytokine production by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of inflammatory cytokine production by... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1602618