Inhibition of jun kinase

Details Inhibition of jun kinase Inhibition of jun kinase

A - Human Necessities

61

K

A61K 31/416 (2006.01) A61K 38/45 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2477842

A method of treating a metabolic disorder associated with insulin resistance by administering to a mammal an inhibitor of a NH2-terminal Jun Kinase (JNK), e.g., a compound or peptide which inhibits JNK1 expression or enzymatic activity.

L'invention concerne un procédé permettant de traiter un trouble métabolique associé à la résistance à l'insuline. Ce procédé consiste à administrer à un mammifère un inhibiteur d'une kinase JNK (NH2-terminal Jun Kinase), par exemple, un composé ou un peptide qui inhibe l'expression de JNK1 ou l'activité enzymatique.

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