Inhibition of leukocyte adhesion

Details Inhibition of leukocyte adhesion Inhibition of leukocyte adhesion

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2159330

This invention relates to the inhibition of intercellular adhesion mediated by L-selectin by administering a newly identified L-selectin ligand, CD34. More particularly, the invention concerns a method for inhibiting leukocyte adhesion to endothelial cells by administering an effective amount of an isolated, purified CD34 polypeptide or an antibody capable of binding native CD34.

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