Inhibition of mac-1 receptor binding to fibrinogen using d30...

Details Inhibition of mac-1 receptor binding to fibrinogen using d30... Inhibition of mac-1 receptor binding to fibrinogen using d30...

C - Chemistry, Metallurgy

07

K

C07K 16/42 (2006.01) A61K 38/36 (2006.01) A61K 39/395 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/75 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2087169

2087169 9201464 PCTABS00010 The present invention contemplates therapeutic compositions containing a D30 homolog capable of binding to the Mac-1 receptor D30 binding site and inhibiting fibrinogen binding to the Mac-1 receptor via the D30 binding site. Methods of inhibiting Mac-1 receptor binding to any Mac-1 ligand and methods of inhibiting Mac-1 receptor mediated inflammation within a patient by administering a D30 homolog are also contemplated.

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