A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2312423
Methods for inhibiting morphogenesis of host cell membrane-budding viruses and infections caused thereby using compounds that inhibit host cell glucosidase or glucosyltransferase enzymes. Methods for treating lipid storage diseases using compounds that inhibit glucosyltransferase enzymes.
La présente invention concerne des procédés permettant d'inhiber, d'une part la morphogénèse de virus bourgeonnant sur la membrane d'une cellule hôte, d'autre part les infections que cela peut provoquer. On utilise à cet effet des composés qui viennent inhiber des enzymes, telles que la glucosidase ou la glucosyltransférase de la cellule hôte. L'invention concerne également le traitement d'affections liées au stockage des lipides, lesquels traitements consistent à utiliser des composés inhibant des enzymes telles que la glucosyltransférase.
Block Timothy M.
Blumberg Baruch S.
Butters Terry D.
Dwek Raymond A.
Mehta Anand
Blumberg Baruch S.
Gowan Intellectual Property
Synergy Pharmaceuticals Inc.
The Chancellor Masters And Scholars Of The University Of Oxford
Thomas Jefferson University
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