Inhibition of migration inhibitory factor in the treatment...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/02 (2006.01) A01K 67/027 (2006.01) A61K 31/56 (2006.01) A61K 31/70 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 14/575 (2006.01) C07K 14/715 (2006.01) C07K 14/72 (2006.01) C07K 16/24 (2006.01) C07K 16/26 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2163211

The present invention relates to compositions and methods for inhibiting the release and/or biological activity of migration inhibitory factor(MIF). In particular, the invention relates to the uses of such compositions and methods for the treatment of various conditions involving cytokine-mediated toxicity, which include, but are not limited to shock, inflammation, graft versus host disease, and/or autoimmune diseases.

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