Inhibition of mineral deposition by phosphorylated and...

C - Chemistry – Metallurgy – 07 – K

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530/7.1, 167/103

C07K 14/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2014051

ABSTRACT OF THE DISCLOSURE A poly-amino acid compound capable of inhibiting mineral deposition, which has the structure: poly (X)m(Y)n where each X independently is aspartate, glutamate, glutamine, asparagine, or anionic derivatives of these amino acids, or phosphoserine, each Y independently is a phosphorylated amino acid such as phosphoserine, phosphohomoserine, phosphotyrosine, phosphothreonine, phosphoglutamine, phosphoasparagine, or mixtures of these residues, m is 2 to 150, n is 1 to 3, and n + m is > 5, and salts of these peptides.

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