Inhibition of mmp-2 activity by oral bacteria and siderophores

Details Inhibition of mmp-2 activity by oral bacteria and siderophores Inhibition of mmp-2 activity by oral bacteria and siderophores

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) A61K 38/55 (2006.01) A61K 7/16 (1995.01)

Patent

CA 2261086

The present invention relates to a composition for preventing and/or treating periodontal diseases. The composition comprises an effective amount of a protease inhibitor, such as a MMP inhibitor or a siderophore, and a pharmaceutically acceptable carrier. The composition may be comprised for example in a toothpaste or a mouthwash formulation. The present invention also relates to a therapeutic method for the prevention and/or treatment of periodontal diseases. The method comprises the step of contacting a protease inhibitor such as a MMP inhibitor or a siderophore with a periodontal tissue.

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