Inhibition of prion protein propagation by receptor...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 25/28 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2755948

A pharmaceutical formulation and method of treatment of prion disease include a RAP agent with a pharmaceuti-cally acceptable carrier and/or excipient, and the administration of same to a subject suffering from or at risk of a prion disease. The RAP agent is an effective means for the prevention and/or treatment of various prion diseases regardless whether the disease is acquired by infection or by genetic mutation.

La présente invention concerne une formulation pharmaceutique et un procédé de traitement de maladie à prion comportant un agent de la protéine associée au récepteur (RAP) avec un support et/ou excipient pharmaceutiquement acceptable, et l'administration de ladite formulation pharmaceutique au sujet atteint ou à risque d'une maladie à prion. L'agent de protéine RAP est un moyen efficace pour la prévention et/ou le traitement de diverses maladies à prion indépendamment du fait que la maladie soit contractée par infection ou mutation génétique.

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