Inhibition of restenosis of ultraviolet radiation

A - Human Necessities – 61 – N

Patent

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A61N 5/06 (2006.01) A61B 17/22 (2006.01) A61M 29/02 (2006.01)

Patent

CA 2092537

2092537 9206741 PCTABS00011 Restenosis following angioplasty can be inhibited by reducing the proliferation of smooth muscle cells in the blood vessel walls at an angioplasty site, and such reduction in cell proliferation can be accomplished by an apparatus which irradiates the angioplasty site with radiation in the ultraviolet (UV) wavelength range. The ultraviolet radiation is preferably delivered via an optical fiber or other waveguide incorporated, for example, into a percutaneous catheter. In operation, the ultraviolet radiation kills smooth muscle cells at the site, thereby reducing the risk of restenosis, while minimizing damage to surrounding tissue.

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