Inhibition of systemic infections in humans and vertebrates...

A - Human Necessities – 61 – K

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A61K 31/736 (2006.01) A23K 1/16 (2006.01) A23L 1/308 (2006.01) A61K 31/715 (2006.01) A61K 31/717 (2006.01) A61K 31/718 (2006.01) A61K 31/731 (2006.01) A61K 31/732 (2006.01) A61K 31/733 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2423783

The use of a dietary fiber or mixture of dietary fibers for the manufacture of a composition, such as a pharmaceutical composition, a functional food or a functional feed, for the prevention, the inhibition and/or treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria is disclosed. A method for preventing and/or inhibiting the systemic growth of pathogenic bacteria in humans and vertebrates, and a method for the prevention, the inhibition and/or the treatment of systemic infections in humans and in vertebrates caused by pathogenic bacteria, comprising administration to said beings a composition containing an effective amount of a dietary fiber or mixture of dietary fibers, are also disclosed. The dietary fiber is preferably a fructan, typically inulin and/or oligofructose, most preferably chicory inulin with an average degree of polymerisation DP of at least 20. The composition and methods are useful for the prevention, inhibition and/or treatment of systemic infections in fish, particularly during cultivation in fish farms.

L'invention concerne l'utilisation d'une fibre alimentaire ou d'un mélange de fibres alimentaires pour la préparation d'une composition, telle qu'une composition pharmaceutique, un aliment fonctionnel ou une pâture fonctionnelle, destinée à la prévention, à l'inhibition et/ou au traitement d'infections systémiques chez des humains et des vertébrés causées par des bactéries pathogènes. L'invention concerne une méthode de prévention et/ou d'inhibition de croissance systémique de bactéries pathogènes chez des humains et des vertébrés, et une méthode de prévention, d'inhibition et/ou de traitement d'infections systémiques chez des humains et des vertébrés causées par des bactéries pathogènes. Ces méthodes consistent à administrer auxdits sujets une composition contenant une quantité effective d'une fibre alimentaire ou d'un mélange de fibres alimentaires. La fibre alimentaire est, de préférence, un fructosane, généralement de l'inuline et/ou un oligofructose, ou mieux encore de l'inuline de chicorée avec un degré de polymérisation moyen (DP) d'au moins 20. La composition et les méthodes de l'invention sont utiles pour la prévention, l'inhibition et/ou le traitement d'infections systémiques chez les poissons, en particulier les poissons élevés en pisciculture.

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