A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/7088 (2006.01) A61P 9/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2470148
The present invention relates to compounds suitable for the treatment of conditions which may be improved, at least in part, by increasing TNF .alpha. production. The invention further relates to assays for the identification of an individual at increased risk for or suffering from such conditions and to methods of screening compounds for their ability to enhance TNF .alpha. biosysthesis.
La présente invention concerne des composés convenant au traitement d'états pouvant être améliorés, au moins en partie, par l'augmentation de la production de TNF.alpha.. Cette invention concerne également des essais permettant d'identifier un individu prédisposé à souffrir ou souffrant de tels états, ainsi que des méthodes de criblage de composés aptes à renforcer la biosynthèse de TNF.alpha..
Braendle Marian
Ehring Thomas
Frohme Marcus
Hentsch Bernd
Hoheisel Joerg Dietrich
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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