Inhibition of tumor growth

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/81 (2006.01) A61K 31/721 (2006.01) A61K 31/724 (2006.01) A61K 31/737 (2006.01) A61K 38/17 (2006.01) A61K 38/57 (2006.01) A61K 47/26 (2006.01) A61K 47/40 (2006.01) C07K 1/14 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/515 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2231952

Anti-angiogenic protein composition can be prepared simply and efficiently by contacting cartilage particles containing the protein together with an electrolyte solution and an oligosaccharide bearing a minimum number of anionic substituents per sugar unit, to extract the anti-angiogenic protein from the cartilage particles and to form a complex of the oligosaccharide and the protein. The resultant anti-angiogenic complex can be used for therapeutic treatment of various angiogenic and related diseases.

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