Inhibition of tumor growth by antisense oligonucleotides for...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/04 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2236825

Oligonucleotides are provided which are effective in inhibiting the growth, metastasis and/or angiogenesis of tumors, including particularly melanoma and/or lung cancer. Methods are also provided for use of these olignonucleotides in the treatment of diseases.

L'invention concerne des oligonucléotides qui permettent d'inhiber avec efficacité la croissance, la métastase et/ou l'angiogenèse des tumeurs, en particulier, des mélanomes et/ou du cancer du poumon. L'invention traite aussi de procédés pour utiliser ces oligonucléotides dans le traitement des maladies.

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