Inhibition of urinary calculi growth

Details Inhibition of urinary calculi growth Inhibition of urinary calculi growth

A - Human Necessities

61

K

A61K 31/66 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2171111

The present invention provides metal ion/bisphosphonate complexes that are useful for the treatment and diagnosis of urinary calculi. Preferred bisphosphonates include etidronate, pamidronate (APD), methylene diphosphonate (MDP), and imidodiphosphonate (IDP). The metal ion is preferably a quadrivalent metal ion such as Sn+4.

L'invention concerne des complexes ions métalliques/biphosphonate utiles pour le traitement et le diagnostic des calculs urinaires. Les biphosphonates préférés sont l'étidronate, le pamidronate (APD), le diphosphonate de méthylène (MDP) et l'imidodiphosphonate (IDP). L'ion métallique est de préférence un ion métallique quadrivalent tel que Sn?+4¿.

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