Inhibition of vascular narrowing using anti-padgen antibodies

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2120240

2120240 9306863 PCTABS00021 A method for inhibiting vascular narrowing at an intravascular site treated by angioplasty, endarterectomy or atherectomy, in natural and synthetic vascular grafts, in arteriovenous fistulas, at intravascular sites following deployment of vascular stents or cardiovascular devices, and at an intravascular site of platelet deposition is disclosed. The method comprises the step of administering a therapeutically effective amount of an anti-PADGEM antibody or an antibody homolog thereof that binds PADGEM.

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