Inhibitor of herpes simplex viral thymidine kinase

Details Inhibitor of herpes simplex viral thymidine kinase Inhibitor of herpes simplex viral thymidine kinase

C - Chemistry, Metallurgy

07

H

C07H 19/073 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01)

Patent

CA 2104895

CT-2191 ABSTRACT Thymidine kinase inhibitor of formula I Image I in which R is C1-6alkyl or Ar(CH2)n-, wherein Ar represents phenyl optionally substituted with one to five same or different halogen, C1-6 alkyl or C1-6 alkyloxy; and n equals one to six. A futher aspect of the present invention provides a method of inhibiting viral thymidine kinase. Yet another aspect of the invention relates to treating herpes simplex viral infections in mammals. Yet another aspect of the invention provides a pharmaceutical formulation. 13

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