Inhibitor of hiv protease

Details Inhibitor of hiv protease Inhibitor of hiv protease

C - Chemistry, Metallurgy

12

P

C12P 13/02 (2006.01) A61K 31/27 (2006.01) C07C 271/22 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2052902

63/RDM34 18206 TITLE OF THE INVENTION INHIBITOR OF HIV PROTEASE ABSTRACT OF THE DISCLOSURE A dipeptide isostere is the biotransformed product after incubation with a culture of Streptomyces. It inhibits HIV protease, and is useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a compound, pharmaceutically acceptable salt, pharmaceutical composition ingredient, whether or not as a prodrug or as a combination with other antivirals, anti- infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

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