Inhibitor proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/15 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2379627

The present invention relates to novel protease inhibitor proteins that have been identified in ticks. These proteins may be used as components of vaccines, as inhibitors of mast cell tryptase, in detection of mast cells and in the isolation and purification of mast cell tryptase. The invention also relates to the control of diseases and injury caused by parasites in animals and humans and to the use of the proteins of the invention in the treatment of certain diseases and allergies.

La présente invention concerne de nouvelles protéines d'inhibiteur de protéase qui ont été identifiées chez des tiques. Ces protéines peuvent être utilisées comme composants de vaccins, comme inhibiteurs de tryptase mastocytaire, dans la détection de mastocytes et dans l'isolement et la purification de tryptase mastocytaire. L'invention a également trait à des moyens permettant de combattre des maladies et des lésions provoquées par des parasites chez l'animal et l'être humain, et à l'utilisation des protéines de l'invention pour traiter certaines maladies et allergies.

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