Inhibitors for use in hemostasis and immune function

Details Inhibitors for use in hemostasis and immune function Inhibitors for use in hemostasis and immune function

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61P 9/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2361273

The present invention relates to polynucleotide and polypeptide molecules for use as inhibitors in hemostasis and immune function. Such inhibitors are members of the family of proteins bearing a collagen-like domain and a globular domain. The inhibitors are useful for promoting blood flow in the vasculature by reducing thrombogenic and complement activity. The inhibitors are also useful for pacify collagenous surfaces and modulating wound healing.

La présente invention concerne des molécules de polynucléotides et de polypeptides pouvant être utilisées comme inhibiteurs dans l'hémostase et la fonction immunitaire. Ces inhibiteurs appartiennent à la famille des protéines portant un domaine de type collagène et un domaine globulaire. Les inhibiteurs de l'invention sont utilisés pour stimuler l'écoulement sanguin dans le système vasculaire en réduisant l'activité thrombogène et l'activité du complément. Ces inhibiteurs sont également utilisés pour rendre inertes les surfaces collagéniques et moduler la cicatrisation.

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