C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4015 (2006.01) A61K 31/4025 (2006.01) A61P 3/10 (2006.01) C07D 207/26 (2006.01) C07D 207/50 (2006.01)
Patent
CA 2646624
The present invention discloses novel compounds of Formula I: (I) having 11 -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11 -HSD type 1 activity.
La présente invention concerne de nouveaux composés représentés par la formule 1: (1) possédant une activité antagoniste 1 de type 11-HSD, ainsi que des procédés de préparation de ces composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques comprenant des composés représentés par la formule 1, ainsi que des procédé d'utilisation de ces composés et de ces compositions pour traiter le diabète, l'hyperglycémie, l'obésité, l'hypertension, l'hyperlipidémie. Le syndrome métabolique et d'autres états associés à l'activité 1 de type 11-HSD.
Bush Julie Kay
Hansen Marvin Martin
Li Renhua
Mabry Thomas Edward
Snyder Nancy June
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1616680